We investigate biological responses to climate change, macrophysiology and evolutionary adaptation, dendroclimatology and ecosystem services. Climate change has a profound influence on global biodiversity. We found that warming causes tropical insects to shrink in size; rapid range shifts are highly associated with levels of climate warming; and global biodiversity redistribution has impacts on ecosystems and human well-being. We are interested in how species adapt to climatic variability. Although competition may often sets elevational range limits of species, we found that short-term temperature variability may dominate how species adapt to climate, which extended the classical climate variability hypothesis. Tropical montane cloud forest is a unique and extremely fragile ecosystem under climate change. We focus on whether the ENSO is still within the range of natural variability over the past millennium, and whether the tropical ecosystems are facing tipping points. Our research combines field work, experimental manipulation and theoretical modeling, big data analysis and deep learning, and we welcome students interested in ecology, climate and data science to join us!