Investigating early-stage diagnosis and targeted therapeutics in cancers – Studying the expression of Aurora-A kinase in cancer cells and developing companion diagnosis and therapy methods
Our study demonstrated that Aurora-A kinase was aberrantly overexpressed in a variety of cancers. By investigating the expression level of Aurora-A gene and its protein translation, we discovered novel therapeutic strategy in the early diagnosis and targeted therapy in cancers. Furthermore, we also studied the correlation between Aurora-A expression level in cancer and tumor immunosuppression.

The role of CPAP protein in liver cancer and its study with inflammatory-related pathways
Tumor microenvironment plays a crucial role in the development and metastasis of liver cancer, which promotes liver cancer growth and malignancy through hyperactivated inflammatory pathways. Our study found that CPAP protein was involved in key inflammatory pathways such as NF-κB and STAT3 which regulate liver cancer progression. By studying the role of CPAP protein in liver cancer progression, we aim to develop novel and effective therapeutic strategy for liver cancer.