Our laboratory is engaged in the research of various optical signal conversion mechanisms, including the study of molecular reaction dynamics and the high-sensitivity surface-enhanced Raman scattering (SERS) detection technology on photonic materials. In terms of biological applications, it combines targeted optical imaging diagnosis and cancer treatment applications. At present, we have established three near-infrared Raman microscopy systems integrated with laser scanning confocal analyzers, which provides powerful equipment for the development of the most innovative nano-optical materials, and the studies were also published in many top international journals. Students in the material group are divided into the Raman substrate group and the colloidal solution group according to the detection methods. They can learn the most advanced nanomaterial synthesis methods and material analysis techniques, and conduct ultra-low detection limit research through Raman microscopy and portable Raman spectroscopy. Recently, we have also studied the application of hot electrons in photocatalysis. Students in the biological group will focus on photothermal and photodynamic therapy research on anticancer and antibacterial treatment. Students can learn antibody/antigen surface modification technique, and understand the mechanism of target delivery and biological signal analysis through the changes of optical signals. We have also established a variety of animal models with near Infrared red stimulation and allows students to learn the most cutting-edge biomedical optoelectronic experiments.