Entry number：15
SUBJECT
The superior physicochemical ambiance provided by Chitin/Carboxylated Chitosan for the formation of hydroxyapatite film
DEPARTMENT
Department of Chemical Engineering
PROFESSOR AND STUDENT
Professor：Ten-Chin Wen
Student：Wei-Cheng Li
ABSTRACT
Chitosan (CS) and chitin (CH) are two natural polysaccharides. Chitosan with different carboxylation degrees rendering specific zwitterionic properties. In this study, carboxylated chitosan (CCS) and CH polymeric matrix was mineralized to form an hydroxyapatite film.
CS grafted carboxylated group at pH 6, 8, and 10 for products denoted as CCS6, CCS8, CCS10. It was the better degrees of carboxylated, the higher ion conductivity. CCS with zwitterion helped ions movement. Based on thermogravimetric analysis, thermal cracking temperature of the amide group on chitin increased after mineralization. In the TEM image, the PILP behavior was found, and formed hexagonal hydroxyapatite beside chitin. The Young's modulus of hydroxyapatite evaluated by AFM was 5.19±0.06GPa. Meanwhile, Ca/P ratio by EDX analysis was 1.65, similar to bones.
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